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王俊儒 
发布时间:2016-04-15  浏览次数:

一、个人简介

 王俊儒,男,陕西杨凌人,中共党员,博士,教授,博士生导师。1987年获兰州大学化学学士学位,在西北农业大学任教迄今。1996年7月获西北农林科技大学土壤学硕士学位;2001年7月获西北农林科技大学植物营养学博士学位。2001年10月-2002年10月、2010年-2011年2次受国家留学基金委资助在英国洛桑试验站学术访问进行环境生物学、化学生物学研究工作。

现任西北农林科技大学理学院副院长,陕西省化学会第十五届理事,省化学会大学生实验教学工作委员会副主任委员。2006年入选教育部“新世纪优秀人才支持计划”,2006年入选“校教学名师支持计划”。2004年获杨凌农业高新产业示范区十大杰出青年称号。

二、科研课题

    近年主持和参与植物资源化学、环境生物学领域研究课题10余项,其中主持校青年学术骨干支持计划1项,教育部新世纪优秀人才计划1项。研究涉及天麻、丹参、黄精和金银花等中草药GAP药源基地建设与指纹图谱质量控制、植物资源化学、生产工艺研究等。在研国家基金1项、校国际合作基金项目1项。

    基于骆驼蓬生物碱为模板的β-咔啉类的二聚化合成、抗癌活性及其机理研究,国家自然基金面上项目,No.31270388,2013.1-2016.12

三、研究领域

1、药用植物资源化学与特殊天然产物生产技术。

2、高活性天然产物结构的鉴定与优化修饰。

3、功能分子和农用化学品合成。

四、高等教育教学

    先后承担有机化学、植物化学、有机立体化学、天然产物化学等本科、研究生6门课程教学。

    在教育教学改革方面,积极推进以能力和素质培养为中心的高等农林院校化学教育改革,负责省级有机化学系列课程教学团队1个,主持省级有机化学双语示范课1门,有机化学省级精品和共享课1门,主持省级教改项目1项、校专业外籍教师英文授课项目1项。近5年主参编国家级规划教材等7部,获省教学成果奖3项。

五、主要科研成果与学术论文

    主要从事药用植物资源化学、天然产物化学生物学研究。涉及天麻、丹参、黄精和金银花等中草药GAP药源基地建设与指纹图谱质量控制、植物资源化学、生产工艺研究,以及相关活性天然产物的结构优化等研究。累计在Phytochemistry, Bioorganic & Medicinal Chemistry Letters, Chem. Commun, Food Chemistry, Plant Physiology等国内外期刊发表天然产物资源化学与功能分子等领域学术论文140篇,其中SCI收录40篇;获发明专利6项。“中药材规范化生产技术体系的建立(07-2-42)”获2008年度陕西省科技进步2等奖,2007年度杨凌示范区科技1等奖。

代表性论文:

1.B. Hao, J.C. Caulfield, M.L. Hamilton, J.A. Pickett, C.A.O. Midega, Z.R. Khan, J. Wang, A.M. Hooper. Biosynthesis of natural and novel C-glycosylflavones utilising recombinant Oryza sativa C-glycosyltransferase (OsCGT) and native D. incanum root proteins. Phytochemistry, 2016

2.Jiang-Kun Dai, Wen-Jia Dan, Na Li, Hong-Tao Du, Ji-Wen Zhang, Jun-Ru Wang. Synthesis, in vitro antibacterial activities of a series of 3-N-substituted canthin-6-ones, Bioorganic & Medicinal Chemistry Letters, 2016, 26: 580–583

3.Hongtao Du, Hongling Gu, Na Li and Junru Wang. Synthesis and biological evaluation of bivalent β-carbolines as potential anticancer agents. MedChemComm, 2016, DOI: 10.1039/C5MD00581G

4.B Hao, JC Caulfield, ML Hamilton, JA Pickett, CAO Midega, ZR Khan, JR Wang, A M Hooper. The biosynthesis of allelopathic di-C-glycosylflavones from the roots of D. incanum (G. Mey.)DC, a drought tolerant intercrop that inhibits Strigahermonthica. Organic & Biomolecular Chemistry, 2015, 13, 11663–11673

5.Jiang-Kun Dai, Wen-Jia Dan, Na Li, Hong-Tao Du, Ji-Wen Zhang, Jun-Ru Wang. Synthesis, in vitro antibacterial activities of a series of 3-N-substituted canthin-6-ones. Bioorganic & Medicinal Chemistry Letters, http://dx.doi.org/10.1016/j.bmcl.2015.11.070

6.Na Li, Jiang-Kun Dai, Hong-Tao Du, Mao-Sen Yuan, Ji-Wen Zhang, Jun-Ru Wang. β-Carboline-functionalized dithioacetal as Hg2+-selective fluorescence probe in water. Spectrochimica Acta Part B: Molecular and Biomolecular Spectroscopy. 2015;136: 900–5

7.Tang D-D, Wang Y, Wang J-R, Xu P-F. Phosphine-Mediated Synthesis of Trifluoromethyl Substituted Pyrroles Using TFAA as the CF3Source. Tetrahedron Letters. 2014;55:4133-5

8.Rongying Qiu, Junru Wang, Kirk L. Parkin. Isolation and identification of cytoprotective agents from nonpolar extracts of buckwheat flour. Food Research International. 2014;66:86-92

9.Yuan M-S, Wang Q, Wang W, Wang D-E, Wang J, Wang J. Truxene-cored π-expanded triarylborane dyes as single-and two-photon fluorescent probes for fluoride. The Analyst. 2014;139(6):1541-9

10.Jun Zhang, Shujun Zhang, Jin Wu, Na Li, Junru Wang. Separation and purification of chlorogenic acid from Lonicera japonica Thunb. leaves exact with macroporous resins. Journal of Medicinal Plants Research, 2013, 7(24), 1784-1792

11.Weiwei Huang, Tiantian He, Chengsen Chai, Yuan Yang, Yahong Zheng, Pei Zhou, Xiaoxia Qiao, Bin Zhang, Zengzhen Liu, Junru Wang, Changhong Shi, Liping Lei, Kun Gao, Hewei Li, Sue Zhong, Libo Yao, Meng-Er Huang, Ming Lei, Triptolide Inhibits the Proliferation of Prostate Cancer Cells and Down-Regulates SUMO-Specific Protease 1 Expression, Plos One, 2012, 7(5), e37693

12.Mao-Sen Yuan, Qi Wang, Wen-Ji Wang, Tian-Bao Li, Lin Wang, Wei Deng, Zhen-ting Du, Jun-Ru Wang, Symmetrical and asymmetrical (multi)branched truxene compounds: Structure and photophysical propertie, Dyes and Pigments, 2012, 95(2), 236-243

13.Yinfen Su, Shengkun Li, Na Li, Liling Chen, Jiwen Zhang and Junru Wang. Seven alkaloids and their antibacterial activity from Hypecoum erectum L. Journal of Medicinal Plants Research, 2011 5(22): 5428-5432

14.Li Ding, Hai Yu, Kam Lau, Saddam Muthana, Junru Wang, Xi Chen. Efficient chemoenzymatic synthesis of sialyl Tn-antigen and derivatives. Chem. Commun., 2011, 47, 8691-8693,

15.Miaofeng Ma, Guohua Hou, Junru Wang, Xumu Zhang. Rhodium-catalyzed asymmetric hydrogenation of b-acetylamino acrylonitriles. Tetrahedron: Asymmetry, 2011, (22) 506–511

16.Miaofeng Ma, Guohua Hou, Tian Sun, Xiaowei Zhang, Wei Li, Junru Wang, Xumu Zhang. Highly Efficient RhI-Catalyzed Asymmetric Hydrogenation of β-Amino Acrylonitriles. Chemistry – A European Journal, 2010, 6(18): 5301-5304

17.Liang Q, Liang ZS, Wang JR, Xu WH. Essential oil composition of Salvia miltiorrhiza flower. Food Chemistry, 2009, 113(2): 592-594

18.Wang J., Zhao F.J., Meharg A.A., Raab A., Feldmann J. and McGrath S.P. Mechanisms of arsenic hyperaccumulation in Pteris vittata: uptake kinetics, interactions with phosphate, and arsenic speciation. Plant Physiology, 2002, 130: 1552-1561. (Highlighted by Plant Physiology On the Inside, “How a Fern Hyperaccumulates As”, 130: 1076)

19.Zhao, F.J., Wang, J.R. Barker, J.H.A., Schat, H., Bleeker, P.M. and McGrath, S.P. The role of phytochelatins in arsenic tolerance in the hyperaccumulator Pteris vittata. New Phytologist, 2003, 159: 403-410. 20.(Highlighted as of special interest by Krämer U. 2005. Phytoremediation: novel approaches to cleaning up polluted soils. Current Opinion in Biotechnology 16:133–141)

21.WANG Jun-ru, PENG Shu-Lin, WANG Ming-Kui, FNG Jun-Tao, DING Li-Sheng, Chemical constituents of the Anemone Tomentosa root. Acta Botanica Sinica, 1999, 41(1):107-110

六、联系方式

通讯地址:陕西杨凌西农路22号,西北农林科技大学北校区理学院18#

办公地址:西北农林科技大学北校区理科楼C206室

邮编:712100

电话:029-87092829; 15109273921

Email: wangjunru@nwsuaf.edu.cn; wangjr07@163.com

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